The #1 issue in desert camping, at least for me, is water. It's heavy and bulky. And it's hard to predict exactly how much you'll need so I usually carry too much just to be safe. Drink lots at the trailhead so you start fully hydrated. Cache it ahead if possible.

Plan your meals so no water is wasted. Cooking pasta in a pot is out. So are meals that require lots of dishes. You can't drink dishwater.