I tried a pair of sock liners years ago, and they did work well, but I never really stuck with it. I've never really had a problem with blisters as my feet seem to be very finicky when it comes to comfortable footwear. I usually have to take a lot of time to find something that fits good for my feet. My socks of choice though, without liners, usually were a wool blend of some sort.

Now, it's like I have liners on all the time. I have to wear compression leggings now all the time, which is a pain, but the ones I have act like a sock liner. They're like pantyhose, except thicker, heavier, and a lot harder to put on. The one thing that I find though it that they are a bit hotter on my feet, and I found that the same with the liners. The wicking part is good, but the heat would get to me on hot days.