If you like Osprey (and I do), take a look at the Volt. I was always partial to the Kestrel series, especially the 48 and 58, but could never get them to fit quite perfectly. I eventually found out that I couldn't get the load lifters to work right; they were attached too low relative to the attachment point of the shoulder straps for me, and I couldn't get more than about a 10 degree angle. They replaced the Kestrel 58 with the Volt 60 - which fits me perfectly. I really, really like the pack (though most would say it's too heavy; personally, I'll carry a "too-heavy" pack if it fits me perfectly.)

If the Volt doesn't fit, take a look at the Atmos series. It also fit me very well; its frame is somewhat external-ish, with a wire bend around the hips that bothered me a bit.

If you can't find anything in the Osprey line you like, take a look at Deuter, especially the ACT Lite series. They are comfortable, supportive, and well-designed.