Sure, Mountain Laurel Designs makes great stuff! I was thinking in terms of packs with frames. For me, a frame that transfers nearly all the weight to the hips and effective load lifters are essential for more than 5 lbs; I have very pressure-sensitive shoulders. YMMV, of course!

I should have included Gossamer Gear, too! Two of their packs (Gorilla and Mariposa) also have frames and the newest editions now have load lifters.

I've undoubtedly left out others; feel free to add them!