I am obviously not OM, but I emailed a professor at Paul Smith's college in the Adirondacks after reading his paper about water quality in the Adirondacks. His paper focused on the effects of acid rain. I asked if he has personally or knows of a study of Adirondack waters and biological contamination in regards to cysts, bacteria, etc... This expert was unaware of any study ever conducted regarding biological contamination of the Adirondack waters. However the DEC still recommends treating, assuming contamination without any evidence. The professor did say that the the results of a study would be fascinating to see if one would ever happen.
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