always wear a poly liner. wicks most of the moisture away, and I rarely get blisters. I'm not sure I've ever had a blister on the trail. They work THAT well for me. Wool sock as a 2nd layer. I believe 100%, high quality wool can absorb 60% of its weight before feeling damp to the touch. In other words, as the poly liner is pulling moisture away, the wool is soaking it up and slowly drying due to body heat. A dry foot is a happy foot.

I also wear a clean pair of poly liners when I go to bed, even in the summer months. A dry foot is a warm (or cool) foot.