I have never weighed my pack directly, I have got on the scale with and without my pack and a few years ago I was at about 40lbs. At the time it wasn't too much discomfort, but since lighter is always more comfortable, I have now got my pack weight down to 30 give or take depending on conditions. I am 5'10" about 190 and train regularly. The conditions your hiking in along with your own condition and age have so much to do with whats comfortable that trial and error and getting lighter whenever possible is what I try to work with.
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"In the beginers mind there are many possibilities, but in the expert's there are few."
Shunryu Suzuki