Yes, I live in middle Tennesee and I have to travel to get any altitude at all. The highest we have around here is around 6300 ft.(in East Tennessee) and I never feel any difference at that altitude, however with that being said, I might experience something different at 8-12,000 ft. I would probably do a little more training and walking and resting if i were to venture above 8000 ft...sabre11004...