You might try a different sock. I used to wade streams in my full leather Asolo boots (long before Goretex liners) wearing either wool or Patagonia socks with little trouble. Once across the stream, I would take off my shoes, wring out the socks, put them back on and keep walking.

I used Second Skin (the gel patches) for minor blisters. As already said, it may be a matter of fit, but different socks may help. A liner sock plus a thick wool or similar sock might keep the sliding around and rubbing to a minimum.
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