part of the problem is that your brain swells "edema" and it is squeesed into your skull tighter than Paris's jeans. At some point this squeesing starts to cut off the blood supply, then going down or being put into a pressurised "barrobag" is the only solution. If only we could build homes with bedrooms that simulated 5,000 of altitude that wouldn't explode at sea level.
Jim
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These are my own opinions based on wisdom earned through many wrong decisions. Your mileage may vary.