O.M. is spot on. What works for me may not work for you. Every foot is different, even when two of them are on the same person!!!

In general, I avoid leather. Takes too long to dry. I'm a horrible overpronator so my shoes must have solid medial support. I need a big toe box because my big toe is really big. Shoes with those features work for me, but not necessarily for you.

Unfortunately the place where you really find out if your shoes are right is several miles and several hours down the trail, not in the store.