There is always that concern with any inflatable. The earliest Neoairs seemed to have some QC issues, but those got fixed pretty fast. POE has had some issues, too. But other than those QC type things, it's mostly just taking care of where you lay it down (moreso in the desert, lava, granite) or not over-inflating it or leaving it in the sun mostly inflated.

I lay my backpad foam (3/16" folded over several times) under my Neoair as extra insurance. The first one I had bought used popped a couple baffles and was replaced for free.