It took me quite a while to get used to the Altras (Lone Peak 3.5), like maybe four or five months of wearing them almost every day, but not exclusively. I suspect that once your calf muscles have stretched out a bit, you can alternate with other shoes as long as you wear the zero drop shoes some of the time. At least, that's what I'm doing. Otherwise, it seems like your calf muscles could shorten up again.

Since you've been wearing the Hokas with a pretty low drop, the Altras shouldn't take too long to get used to.

Regarding cushioning, since Pika mentioned it, the Altras have plenty of cushioning. The Torin and Paradigm are road runners as opposed to trailrunners, but both types are well cushioned. Some models have less cushion than others, but their web site has that information for the different models.