I'd nix the Nalgene bottle in favor of a water bladder...1 l minimum. and you'll want another one for dirty water feed to the sawyer mini. also repack the toiletries/first aid bag. take only a reasonable amount of any cream ( pour into small squeeze bottles(available on line, in many sizes).. and ditch the first aid bag...you already know they're first aid supplies. all placed inside a size appropriate ziplock bag. loose the t.p. cardboard roll unless if it serves a second purpose. now for the fun stuff where DO you hike and seasons?