I'm usually awake part of the first night listening to the night sounds, really welcome and exciting after the city noise at home. I just assume that on day 2 I'll be a bit sleep-deprived. After that, no problems! The only issue would be on a one-night trip with a long drive home on day 2, a situation I avoid.

The problem with prescription sleep aids is if you have to get up at night, you will be staggering around quite zonked and could get into trouble.
May your trails be crooked, winding, lonesome, dangerous, leading to the most amazing view--E. Abbey