I have tried dozens of pairs of footwear from mountaineering boots (massive, heavy, nearly rigid), to early generation light weight hikers to modern light weight ankle highs.
I have just bought my first pair of trail runners (actually bought for Tough Mudders but they can do double duty). I have yet to try them, but I think they would be a little fragile for much hiking. Have not even had them on yet, but the top fabric seems a little fragile, inviting a big toenail to poke through.
I own too many shoes, but why wouldn't you want to change up for different conditions?