I'm usually awake part of the first night listening to the night sounds, really welcome and exciting after the city noise at home. I just assume that on day 2 I'll be a bit sleep-deprived. After that, no problems! The only issue would be on a one-night trip with a long drive home on day 2, a situation I avoid.

The problem with prescription sleep aids is if you have to get up at night, you will be staggering around quite zonked and could get into trouble.
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May your trails be crooked, winding, lonesome, dangerous, leading to the most amazing view--E. Abbey